Lerociclib (G1T38)
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Important Notice: For research use only. We do not sell to patients.
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Discription | Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. | ||
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Targets |
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Catalog Num | A18320 |
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Formula | C26H34N8O |
Molecular Weight | 474.613 |
CAS Number | 1628256-23-4 |
SMILES | CC(C)N(CC1)CCN1C(C=N2)=CC=C2NC3=NC=C4C(N(C5(CCCCC5)CNC6=O)C6=C4)=N3 |
Synonyms | G1T-38, G1 T38 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 2 mg/mL (4.21 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.07 mL | 105.35 mL | 210.7 mL |
0.5 mM | 4.21 mL | 21.07 mL | 42.14 mL |
1 mM | 2.11 mL | 10.53 mL | 21.07 mL |
5 mM | 0.42 mL | 2.11 mL | 4.21 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2