SAR156497
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | SAR156497 is an exquisitely selective Aurora A, B, and C inhibitor with in vitro and in vivo efficacy with IC50 = 0.5 nM (Aurora A), 1 nM (Aurora B / incenp), 3 nM (Aurora C / incenp) respectively SAR156497 combines high in vitro potency with satisfactory metabolic stability and limited CYP3A4 and PDE3 inhibition. |
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Catalog Num | A14382 |
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Formula | C27H24N4O4 |
Molecular Weight | 468.5 |
CAS Number | 1256137-14-0 |
SMILES | O=C(C1=C2NC3=C(C(CCC3)=O)[C@@H](C4=CC=CC(OC5=NC6=CC=CC=C6N5)=C4)C2=CN1)OCC |
Synonyms | SAR-156497, SAR 156497 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2