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TRK, ROS1, ALK inhibitor

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Catalog No. A15801

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Entrectinib 5mg A15801-5
Entrectinib 10mg A15801-10
Entrectinib 25mg A15801-25

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity.


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Chemical Information

Catalog Num A15801
Actions Inhibitor
M. Wt 560.64
Formula C31H34F2N6O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1108743-60-7
Synonyms RXDX-101, RXDX-101, RXDX-101, NMS E628, NMS-E628, NMSE628

Biological Activity

Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.84 mL 89.18 mL 178.37mL
0.5 mM 3.57 mL 17.84 mL 35.67 mL
1 mM 1.78 mL 8.92 mL 17.84 mL
5 mM 0.36 mL 1.78 mL 3.57 mL

*The above data is based on the productmolecular weight 560.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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