Total item
Cart Subtotal
$0.00 Biological Activity
Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity.
Targets
| TrkA | TrkB | TrkC | ROS1 | ALK |
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.84 mL | 89.18 mL | 178.37 mL |
| 0.5 mM | 3.57 mL | 17.84 mL | 35.67 mL |
| 1 mM | 1.78 mL | 8.92 mL | 17.84 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.57 mL |
*The above data is based on the productmolecular weight 560.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Chemical Properties
| Catalog Num | A15801 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 560.64 |
| Formula | C31H34F2N6O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1108743-60-7 |
| Synonyms | RXDX-101, RXDX-101, RXDX-101, NMS E628, NMS-E628, NMSE628 |
| SMILES | CN1CCN(CC1)C2=CC(=C(C=C2)C(=O)NC3=NNC4=C3C=C(C=C4)CC5=CC(=CC(=C5)F)F)NC6CCOCC6 |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Entrectinib | Entrectinib Supplier | purchase Entrectinib | Entrectinib cost | Entrectinib manufacturer | order Entrectinib | Entrectinib distributor | buy 1108743-60-7| 1108743-60-7 Supplier | purchase 1108743-60-7 | 1108743-60-7 cost | 1108743-60-7 manufacturer | order 1108743-60-7 | 1108743-60-7 distributor
Adooq Quality Guarantee
We promise all products perform as described.