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|Storage||at -20°C 3 years Powder|
|SMILES code||C[[email protected]]1CCC[[email protected]@]2([[email protected]@H](O2)C[[email protected]](OC(=O)C[[email protected]@H](C(C(=O)[[email protected]@H]([[email protected]]1O)C)(C)C)O)/C(=C/C3=CSC(=N3)C)/C)C|
|Chemical Name||(1S,3S,7S,10R,11S,12S,16R)-7,11-Dihydroxy-8,8,10,12,16- pentamethyl-3-[(1E)-1-methyl-2-(2-methyl-4-thiazolyl)et henyl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione|
|Epothilone B is a macrolide that causes the formation of bundles of intracellular microtubules in non-mitotic cells, induces the formation of hyperstable tubulin polymers, and arrests cell cycling in mitosis.|
|Solubility (25°C) *||In vitro||DMSO||102 mg/mL (200.91 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||102 mg/mL (200.91 mM)|
|In vivo||30% PEG400/0.5% Tween80/5% propylene glycol||5 mg/mL|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||19.7 mL||98.48 mL||196.97mL|
|0.5 mM||3.94 mL||19.7 mL||39.39 mL|
|1 mM||1.97 mL||9.85 mL||19.7 mL|
|5 mM||0.39 mL||1.97 mL||3.94 mL|
*The above data is based on the productmolecular weight 507.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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