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|Storage||at -20°C 3 years Powder|
|Synonyms||GDC 0349, RG7603|
|SMILES code||CCNC(=O)NC1=CC=C(C=C1)C2=NC3=C(CCN(C3)C4COC4)C(=N2)N5CCOC[[email protected]@H]5C|
|GDC-0349 is under evaluating the Safety and Tolerability in Patients with locally advanced or metastatic solid tumors or non hodgkin's lymphoma.|
|Solubility (25°C)*||In vitro||DMSO||91 mg/mL (201.08 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||6 mg/mL (13.25 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||22.09 mL||110.47 mL||220.95mL|
|0.5 mM||4.42 mL||22.09 mL||44.19 mL|
|1 mM||2.21 mL||11.05 mL||22.09 mL|
|5 mM||0.44 mL||2.21 mL||4.42 mL|
*The above data is based on the productmolecular weight 452.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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