GKT137831

Name: GKT137831
SKU: A14433
Price: 72 USD
Rating: 5 (1 reviews)

Catalog No.: A14433

NOX1/4 inhibitor

Adooq's GKT137831 has been cited by 1 publications

GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes.

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Grouped product items
Product Name	Price	Stock
GKT137831 5mg	Special Price $72.00 Regular Price $90.00	In stock
GKT137831 10mg	Special Price $112.00 Regular Price $140.00	In stock
GKT137831 25mg	Special Price $256.00 Regular Price $320.00	In stock
*GKT137831 10mM 1mL in DMSO**	Special Price $80.00 Regular Price $100.00	In stock
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Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's GKT137831 has been cited by 1 publications

Chia-Hui Huang, .et al. , Toxicol Appl Pharmacol, 2020, Apr 17;397:115013 PMID: 32305283

Biological Activity

Discription

GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes.

Targets

Target	Value

Product Information

Catalog Num	A14433
Formula	C21H19ClN4O2
Molecular Weight	394.85
CAS Number	1218942-37-0
SMILES	CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl
Synonyms	GKT-137831, GKT 137831
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	Warmed: 72 mg/mL (182.34 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+2% Tween 80+30% PEG 300+ddH2O	8 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.33 mL	126.63 mL	253.26 mL
0.5 mM	5.07 mL	25.33 mL	50.65 mL
1 mM	2.53 mL	12.66 mL	25.33 mL
5 mM	0.51 mL	2.53 mL	5.07 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂