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Publications citing Adooq Products
Chemical Information
| Catalog Num | A14433 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 394.85 |
| Formula | C21H19ClN4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1218942-37-0 |
| Synonyms | GKT-137831, GKT 137831 |
| SMILES code | CN1C(=O)C=C2C(=C1C3=CC(=CC=C3)N(C)C)C(=O)N(N2)C4=CC=CC=C4Cl |
| Chemical Name | N/A |
Description |
GKT137831 is a first in class inhibitor targeting NOX1 and NOX4 enzymes. | ||||||||||
Targets |
|
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| Solubility (25°C)* | In vitro | DMSO | 78 mg/mL heating (197.54 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.33 mL | 126.63 mL | 253.26mL |
| 0.5 mM | 5.07 mL | 25.33 mL | 50.65 mL |
| 1 mM | 2.53 mL | 12.66 mL | 25.33 mL |
| 5 mM | 0.51 mL | 2.53 mL | 5.07 mL |
*The above data is based on the productmolecular weight 394.85. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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