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Retosiban (GSK-221,149-A) is an oral drug which acts as a selective, sub-nanomolar (Ki = 0.65 nM) oxytocin receptor antagonist with >1400-fold selectivity[3] over the related vasopressin receptors
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.22 mL | 101.1 mL | 202.19 mL |
| 0.5 mM | 4.04 mL | 20.22 mL | 40.44 mL |
| 1 mM | 2.02 mL | 10.11 mL | 20.22 mL |
| 5 mM | 0.4 mL | 2.02 mL | 4.04 mL |
*The above data is based on the productmolecular weight 494.58. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13106 |
|---|---|
| Actions | Antagonist |
| CAS No. | 820957-38-8 |
| Formula | C27H34N4O5 |
| M. Wt | 494.58 |
| Purity | >98% |
| Synonyms | GSK-221149A, GSK 221149A |
| SMILES | CC[[email protected]](C)[[email protected]@H]1C(=O)N[[email protected]@H](C(=O)N1[[email protected]](C2=COC(=N2)C)C(=O)N3CCOCC3)C4CC5=CC=CC=C5C4 |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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