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NaV1.3 and NaV1.1 channels inhibitor

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Catalog No. A13773

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
ICA-121431 10mg A13773-10

Regular Price: $95.00

Special Price: $85.50

ICA-121431 25mg A13773-25

Regular Price: $190.00

Special Price: $171.00

ICA-121431 50mg A13773-50

Regular Price: $280.00

Special Price: $252.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

ICA-121431 is a potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23 nM respectively).


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Chemical Information

Catalog Num A13773
Actions Inhibitor
M. Wt 449.55
Formula C23H19N3O3S2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 313254-51-2
Synonyms ICA 121431, ICA121431
SMILES code C1=CC=C(C=C1)C(C2=CC=CC=C2)C(=O)NC3=CC=C(C=C3)S(=O)(=O)NC4=NC=CS4
Chemical Name a-Phenyl-N-[4-[(2-thiazolylamino)sulfonyl]phenyl]benzeneacetamide

Biological Activity

ICA-121431 is a potent and selective inhibitor of human NaV1.3 and NaV1.1 channels (IC50 values are 13 and 23 nM respectively).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.24 mL 111.22 mL 222.44mL
0.5 mM 4.45 mL 22.24 mL 44.49 mL
1 mM 2.22 mL 11.12 mL 22.24 mL
5 mM 0.44 mL 2.22 mL 4.45 mL

*The above data is based on the productmolecular weight 449.55. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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