Iguratimod (T 614)

Catalog No.: A11464

COX-2 inhibitor

Iguratimod (T 614)

Iguratimod (T 614) Chemical Structure

CAS NO. 123663-49-0

Iguratimod(T 614) is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. Iguratimod(T 614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor.

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5 mg

Regular Price: $45.00

Special Price $36.00

10 mg

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25 mg

Regular Price: $140.00

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50 mg

Regular Price: $225.00

Special Price $180.00

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Biological Activity

Iguratimod(T 614) is one of a series of 4H-1-benzopyran-4-ones which has potent anti-inflammatory, analgesic and antipyretic activity. Iguratimod(T 614) is a selective inhibitor of cyclo-oxygenase-2 (COX-2), and inhibits the production of interleukin-1 (IL-1), IL-6, IL-8 and tumour necrosis factor.
In vitro DMSO 46 mg/mL (122.87 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.71 mL 133.56 mL 267.12 mL
0.5 mM 5.34 mL 26.71 mL 53.42 mL
1 mM 2.67 mL 13.36 mL 26.71 mL
5 mM 0.53 mL 2.67 mL 5.34 mL

*The above data is based on the productmolecular weight 374.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11464
Actions Inhibitor
CAS No. 123663-49-0
Formula C17H14N2O6S
M. Wt 374.37
Purity >98%
Synonyms T614
SMILES CS(=O)(=O)NC1=C(C=C2C(=C1)OC=C(C2=O)NC=O)OC3=CC=CC=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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