LRRK2-IN-1
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively. | ||
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Targets |
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Catalog Num | A11477 |
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Formula | C31H38N8O3 |
Molecular Weight | 570.09 |
CAS Number | 1234480-84-2 |
SMILES | CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 97 mg/mL (169.96 mM) | |
Water | Insoluble | ||
Ethanol | 97 mg/mL (169.96 mM) | ||
In vivo | Captisol | 16 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 17.54 mL | 87.71 mL | 175.41 mL |
0.5 mM | 3.51 mL | 17.54 mL | 35.08 mL |
1 mM | 1.75 mL | 8.77 mL | 17.54 mL |
5 mM | 0.35 mL | 1.75 mL | 3.51 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2