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LRRK2 inhibitor

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Catalog No. A11477

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
LRRK2-IN-1 10mg A11477-10

Regular Price: $110.00

Special Price: $99.00

LRRK2-IN-1 25mg A11477-25

Regular Price: $230.00

Special Price: $207.00

LRRK2-IN-1 50mg A11477-50

Regular Price: $400.00

Special Price: $360.00

LRRK2-IN-1 10mM * 1mL in DMSO A11477-10mM-D

Regular Price: $120.00

Special Price: $108.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively.


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Chemical Information

Catalog Num A11477
Actions Inhibitor
M. Wt 570.09
Formula C31H38N8O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1234480-84-2
Synonyms N/A

Biological Activity

LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively.
Target Value
DCLK1IC50: 2.61nM
LRRK2(G2019S)IC50: 6nM
LRRK2(WT)IC50: 13nM
DCLK2IC50: 45nM
LRRK2(A2016T)IC50: 2.45μM
LRRK2(A2016T+G2019S)IC50: 3.08μM

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.54 mL 87.71 mL 175.41mL
0.5 mM 3.51 mL 17.54 mL 35.08 mL
1 mM 1.75 mL 8.77 mL 17.54 mL
5 mM 0.35 mL 1.75 mL 3.51 mL

*The above data is based on the productmolecular weight 570.09. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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