LRRK2-IN-1

Name: LRRK2-IN-1
SKU: A11477
Price: 55 USD
Rating: 5 (288 reviews)

Catalog No.: A11477

LRRK2 inhibitor

LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
Size	Price	Stock
5mg	$55.00	In stock
10mg	$80.00	In stock
25mg	$170.00	In stock
50mg	$315.00	In stock
100mg	$555.00	In stock
500mg	$1,900.00	In stock
*10mM 1mL in DMSO**	$80.00	In stock
Bulk Size	Bulk Discount

Bulk Inquiry

Notify me when the price drops

Free Delivery on orders over $500

Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

Loading distributor info...

Adooq Products cited in reputable paper

Biological Activity

Discription

LRRK2-IN-1 inhibits both G2019S mutant and wild-type LRRK2 kinase activity with IC50 values of 6 and 13 nM respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

Product Information

Catalog Num	A11477
Formula	C31H38N8O3
Molecular Weight	570.09
CAS Number	1234480-84-2
SMILES	CN1CCN(CC1)C2CCN(CC2)C(=O)C3=CC(=C(C=C3)NC4=NC=C5C(=N4)N(C6=CC=CC=C6C(=O)N5C)C)OC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	97 mg/mL (169.96 mM)
	Water	Insoluble
	Ethanol	97 mg/mL (169.96 mM)
In vivo	Captisol	16 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.54 mL	87.71 mL	175.41 mL
0.5 mM	3.51 mL	17.54 mL	35.08 mL
1 mM	1.75 mL	8.77 mL	17.54 mL
5 mM	0.35 mL	1.75 mL	3.51 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂