LY2603618 (IC-83)

Catalog No.: A11036

Chk inhibitor

LY2603618 (IC-83)

LY2603618 (IC-83) Chemical Structure

CAS NO. 911222-45-2

LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $90.00

Special Price $72.00

10 mg

Regular Price: $140.00

Special Price $112.00

50 mg

Regular Price: $420.00

Special Price $336.00

100 mg

Regular Price: $700.00

Special Price $560.00

10mM * 1mL in DMSO
$95.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Details

LY2603618 is a chk2 inhibitor that binds to and inhibits the activity of chk2, which may prevent the repair of DNA caused by DNA-damaging agents.
Targets
Chk1 (Cell-free assay)
In vitro (25°C) DMSO 13 mg/mL (29.79 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 2% DMSO, 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.92 mL 114.6 mL 229.2 mL
0.5 mM 4.58 mL 22.92 mL 45.84 mL
1 mM 2.29 mL 11.46 mL 22.92 mL
5 mM 0.46 mL 2.29 mL 4.58 mL

*The above data is based on the productmolecular weight 436.3 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Technical Details

Catalog Num A11036
Actions Inhibitor
M. Wt 436.3
Formula C18H22BrN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 911222-45-2
Synonyms LY-2603618
SMILES CC1=CC(=C(C=C1Br)NC(=O)NC2=NC=C(N=C2)C)OC[[email protected]@H]3CNCCO3

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