Customer Appreciation Sale.
15% off with promo code "APPRECIATION2023" on check out or purchase order
Biological Activity
LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.
In vitro | DMSO | 22 mg/mL (49.04 mM) | |
Water | Insoluble | ||
Ethanol | 40 mg/mL (89.16 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.29 mL | 111.46 mL | 222.92 mL |
0.5 mM | 4.46 mL | 22.29 mL | 44.58 mL |
1 mM | 2.23 mL | 11.15 mL | 22.29 mL |
5 mM | 0.45 mL | 2.23 mL | 4.46 mL |
*The above data is based on the productmolecular weight 448.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15823 |
---|---|
Actions | Inhibitor |
CAS No. | 1619903-54-6 |
Formula | C26H36N6O |
M. Wt | 448.6 |
Purity | >98% |
Synonyms | LY-2857785, LY 2857785 |
SMILES | CC(C)C1=C2C=C(C=CC2=NN1C)C3=NC(=NC=C3)NC4CCC(CC4)NC5CCOCC5 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
Indirubin
Indirubin, the active constituent of a Chinese antileukaemia medicine, is a potent cyclin-dependent kinases and GSK-3β inhibitor with IC50 …
CGP60474
CGP60474 is a potent inhibitor of cyclin-dependent kinase (CDK).
AT7519 trifluoroacetate
AT7519 trifluoroacetate is a multi-CDK inhibitor for CDK1, 2, 4, 6 and 9 with IC50 of 10-210 nM, less potent to CDK3 and little active to CD…
JNJ-7706621
JNJ-7706621 is pan-CDK inhibitor with the highest potency on CDK1/2 with IC50 of 9 nM/4 nM and showing >6-fold selectivity for CDK1/2 than C…
LEE011 (Ribociclib)
LEE011 is an orally available cyclin-dependent kinase (CDK) inhibitor targeting cyclin D1/CDK4 and cyclin D3/CDK6 cell cycle pathway, with p…
PD 0332991 HCl (Palbociclib)
PD 0332991 HCl is an orally available pyridopyrimidine-derived cyclin-dependent kinase (CDK) inhibitor with potential antineoplastic activit…
Kenpaullone
Kenpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ = 400 nM), CDK2/cyclin A (IC₅₀ = 680nM) , CDK5 (IC₅₀ = 850nM) and with …
Purvalanol A
Purvalanol A is a potent, cell-permeable cyclin-dependent protein kinase (cdk) inhibitor. IC50 values are 4, 70, 35, 850 and 75 nM for cdc2/…
Keywords:buy LY2857785 | LY2857785 Supplier | purchase | cost | manufacturer | order | distributor | buy 1619903-54-6| 1619903-54-6 Supplier | purchase 1619903-54-6 | 1619903-54-6 cost | 1619903-54-6 manufacturer | order 1619903-54-6 | 1619903-54-6 distributor