LY2857785

Catalog No.: A15823

CDK9 inhibitor

LY2857785 Chemical Structure

CAS NO. 1619903-54-6

LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.

Availability: In stock

Package Price Qty
5 mg
$240.00
10 mg
$390.00
25 mg
$800.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

LY2857785 is a potent and selective CDK9 inhibitor; significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.29 mL 111.46 mL 222.92 mL
0.5 mM 4.46 mL 22.29 mL 44.58 mL
1 mM 2.23 mL 11.15 mL 22.29 mL
5 mM 0.45 mL 2.23 mL 4.46 mL

*The above data is based on the productmolecular weight 448.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15823
Actions Inhibitor
M. Wt 448.6
Formula C26H36N6O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1619903-54-6
Synonyms LY-2857785, LY 2857785
SMILES CC(C)C1=C2C=C(C=CC2=NN1C)C3=NC(=NC=C3)NC4CCC(CC4)NC5CCOCC5

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