ML 171

Catalog No.: A13360

NOX1 inhibitor

ML 171

ML 171 Chemical Structure

CAS NO. 6631-94-3

ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.

Availability: In stock

Package Price Qty
100 mg
$40.00
250 mg
$80.00
500 mg
$90.00
1000 mg
$150.00
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Biological Activity

ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.
In vitro DMSO 44 mg/mL (182.33 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.44 mL 207.2 mL 414.4 mL
0.5 mM 8.29 mL 41.44 mL 82.88 mL
1 mM 4.14 mL 20.72 mL 41.44 mL
5 mM 0.83 mL 4.14 mL 8.29 mL

*The above data is based on the productmolecular weight 241.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13360
Actions Inhibitor
CAS No. 6631-94-3
Formula C14H11NOS
M. Wt 241.31
Solubility DMSO
Purity >98%
Synonyms ML-171, ML171
SMILES CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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