ML 171

Catalog No.: A13360

NOX1 inhibitor

ML 171

ML 171 Chemical Structure

CAS NO. 6631-94-3

ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.

Availability: In stock

Package Price Qty
100 mg
$40.00
250 mg
$80.00
500 mg
$90.00
1000 mg
$150.00
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Biological Activity

ML171 (2-Acetylphenothiazine;2-APT) is a potent and selective NADPH oxidase 1 (Nox1) inhibitor that blocks Nox1-dependent ROS generation, with an IC50 of 0.25 μM in HEK293-Nox1 confirmatory assay.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 41.44 mL 207.2 mL 414.4 mL
0.5 mM 8.29 mL 41.44 mL 82.88 mL
1 mM 4.14 mL 20.72 mL 41.44 mL
5 mM 0.83 mL 4.14 mL 8.29 mL

*The above data is based on the productmolecular weight 241.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13360
Actions Inhibitor
M. Wt 241.31
Formula C14H11NOS
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 6631-94-3
Synonyms ML-171, ML171
SMILES CC(=O)C1=CC2=C(C=C1)SC3=CC=CC=C3N2

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