ML 786 dihydrochloride

Catalog No.: A11211

Raf inhibitor

ML 786 dihydrochloride

ML 786 dihydrochloride Chemical Structure

CAS NO. 1237536-18-3

ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).

Availability: In stock

Package Price Qty
5 mg
$150.00
10 mg
$250.00
50 mg
$800.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

ML 786 dihydrochloride is a potent Raf kinase inhibitor (IC50 values are 2.1, 2.5 and 4.2 nM for B-RafV600E, C-Raf and wild-type B-Raf respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.35 mL 81.77 mL 163.54 mL
0.5 mM 3.27 mL 16.35 mL 32.71 mL
1 mM 1.64 mL 8.18 mL 16.35 mL
5 mM 0.33 mL 1.64 mL 3.27 mL

*The above data is based on the productmolecular weight 611.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11211
Actions Inhibitor
M. Wt 611.48
Formula C29H29F3N4O3.2HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1237536-18-3
Synonyms ML786 dihydrochloride
SMILES CC(C)(C1=CC(=CC(=C1)C(=O)NC2CCC3=C(C2)C=C(C=C3)OC4=C5CCC(=O)NC5=NC=C4)C(F)(F)F)N.Cl.Cl

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