MLN2480 (BIIB-024)

Catalog No.: A11240

pan-Raf inhibitor

MLN2480 (BIIB-024)

MLN2480 (BIIB-024) Chemical Structure

CAS NO. 1096708-71-2

MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.

Availability: In stock

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5 mg

Regular Price: $150.00

Special Price $120.00

10 mg

Regular Price: $250.00

Special Price $200.00

25 mg

Regular Price: $480.00

Special Price $384.00

50 mg

Regular Price: $800.00

Special Price $640.00

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Biological Activity

MLN 2480 is an oral, selective pan-Raf kinase inhibitor in chinical trials.
Targets
Raf
In vitro DMSO 95 mg/mL (187.63 mM)
Water 95 mg/mL (187.63 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.75 mL 98.76 mL 197.52 mL
0.5 mM 3.95 mL 19.75 mL 39.5 mL
1 mM 1.98 mL 9.88 mL 19.75 mL
5 mM 0.4 mL 1.98 mL 3.95 mL

*The above data is based on the productmolecular weight 506.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11240
Actions Inhibitor
CAS No. 1096708-71-2
Formula C17H12Cl2F3N7O2S
M. Wt 506.29
Purity >98%
Synonyms MLN-2480,BIIB 024, BIIB-024
SMILES C[[email protected]](C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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