MP470 (MP-470, Amuvatinib)

Catalog No.: A10610

RTK inhibitor

MP470 (MP-470, Amuvatinib) Chemical Structure

CAS NO. 850879-09-3

MP470 is a c-Kit/PDGFR tyrosine kinase inhibitor.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $100.00

Special Price $80.00

10 mg

Regular Price: $165.00

Special Price $132.00

50 mg

Regular Price: $485.00

Special Price $388.00

10mM * 1mL in DMSO
$120.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MP470 is a c-Kit/PDGFR tyrosine kinase inhibitor.
Targets
c-Kit (D816H) PDGFRα (V561D) FLT3 (D835Y)
10 nM40 nM81 nM
In vitro (25°C) DMSO 32 mg/mL (71.5 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.35 mL 111.73 mL 223.46 mL
0.5 mM 4.47 mL 22.35 mL 44.69 mL
1 mM 2.23 mL 11.17 mL 22.35 mL
5 mM 0.45 mL 2.23 mL 4.47 mL

*The above data is based on the productmolecular weight 447.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10610
Actions Inhibitor
M. Wt 447.5
Formula C23H21N5O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 850879-09-3
Synonyms Amuvatinib
SMILES C1CN(CCN1C2=NC=NC3=C2OC4=CC=CC=C43)C(=S)NCC5=CC6=C(C=C5)OCO6

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