Norfluoxetine

Catalog No.: A13458

serotonin uptake inhibitor

Norfluoxetine

Norfluoxetine Chemical Structure

CAS NO. 83891-03-6

Norfluoxetine is an active metabolite of the antidepressant fluoxetine that inhibits serotonin uptake with a pKi value of 7.35.1 The S-enantiomer of norfluoxetine has 20-times higher serotonin reuptake blocking potency than the R-enantiomer (pKis = 7.86 versus 6.51, respectively).

Availability: In stock

Package Price Qty
5 mg
$120.00
10 mg
$200.00
25 mg
$420.00
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Biological Activity

Norfluoxetine is an active metabolite of the antidepressant fluoxetine that inhibits serotonin uptake with a pKi value of 7.35.1 The S-enantiomer of norfluoxetine has 20-times higher serotonin reuptake blocking potency than the R-enantiomer (pKis = 7.86 versus 6.51, respectively).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 33.86 mL 169.32 mL 338.64 mL
0.5 mM 6.77 mL 33.86 mL 67.73 mL
1 mM 3.39 mL 16.93 mL 33.86 mL
5 mM 0.68 mL 3.39 mL 6.77 mL

*The above data is based on the productmolecular weight 295.30. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13458
Actions Inhibitor
CAS No. 83891-03-6
Formula C16H16F3NO
M. Wt 295.30
Purity >98%
Synonyms Desmethylfluoxetine
SMILES C1=CC=C(C=C1)C(CCN)OC2=CC=C(C=C2)C(F)(F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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