Norovirus Group-1 P-Domain
Catalog No.: AP6257
Norovirus Group-1 Capsid P-Domain Recombinant
The Recombinant Norovirus Group-1 Capsid P-Domain, E.Coli derived, Norwalk strain contains a.a. from 225-520 having a Mw of 30kDa. The protein is fused to a 6xHis tag at N-terminal and purified by chromatography techniques.
P-domain (225-520 a.a.) forms P1- P2-P1 structure. P-domain has a receptor binding region to recognize human histo-blood group antigens (HBGAs). P-domain expressed in
bacteria can spontaneously form a P dime and a P particle aggregated by 12 P dimmers. P-particle displays an enhanced binding activity to HBGAs higher than virus-like particle
(VLP) formed by the full length capsid.
For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.
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