NVP-BEP800

Catalog No.: A10660

HSP90 Inhibitor

NVP-BEP800

NVP-BEP800 Chemical Structure

CAS NO. 847559-80-2

NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH2-terminal ATP-binding pocket of Hsp90.

Availability: In stock

Package Price Qty
5 mg
$100.00
10 mg
$180.00
25 mg
$350.00
100 mg
$1,000.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

NVP-BEP800 is a novel, fully synthetic, orally bioavailable inhibitor that binds to the NH2-terminal ATP-binding pocket of Hsp90.
Targets
HSP90β
58 nM
In vitro (25°C) DMSO <1 mg/mL (<1 mM)
Water <1 mg/mL (<1 mM)
Ethanol 15 mg/mL (31.22 mM)
In vivo 0.5% methylcellulose 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.82 mL 104.08 mL 208.16 mL
0.5 mM 4.16 mL 20.82 mL 41.63 mL
1 mM 2.08 mL 10.41 mL 20.82 mL
5 mM 0.42 mL 2.08 mL 4.16 mL

*The above data is based on the productmolecular weight 480.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10660
Actions Inhibitor
M. Wt 480.4
Formula C21H23Cl2N5O2S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 847559-80-2
Synonyms VER-82576
SMILES CCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4

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