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PD0325901

Catalog No.: A10256
MEK inhibitor
Adooq's PD0325901 has been cited by 6 publications
PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.
PD0325901
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Product Name Price Stock Qty
PD0325901 5mg
$45.00
In stock
PD0325901 10mg
$90.00
In stock
PD0325901 25mg
$150.00
In stock
PD0325901 100mg
$310.00
In stock
PD0325901 10mM * 1mL in DMSO
$60.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's PD0325901 has been cited by 6 publications
  • Tadaaki Nakajima, .et al. , FEBS Open Bio, 2024, Jan;14(1):37-50 PMID: 37953493
  • Jan Langkabel, .et al. , bioRxiv, 2021, January 25
  • Ryan Clarke, .et al. , Mol Cell, 2021, Jan 21;81(2):226-238.e5 PMID: 33378644
  • Tzeng SF, .et al. , FASEB J, 2018, Jun 15:fj201800687 PMID: 29906246
  • Fukumoto S, .et al. , Acta Histochem, 2018, Feb;120(2):142-150 PMID: 29397960
  • Yoshiteru Yano, .et al. , Regenerative Therapy, 2016, 3 (2016) 1-6
    • Biological Activity
    Discription PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.
    Targets
    Target Value
    Product Information
    Catalog Num A10256
    Formula C16H14F3IN2O4
    Molecular Weight 482.2
    CAS Number 391210-10-9
    SMILES C1=CC(=C(C=C1I)F)NC2=C(C=CC(=C2F)F)C(=O)NOC[C@@H](CO)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 89 mg/mL (184.57 mM)
    Water Insoluble
    Ethanol 37 mg/mL (76.73 mM)
    In vivo 5%DMSO+40%PEG300+5%Tween80+50%ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 20.74 mL 103.69 mL 207.38 mL
    0.5 mM 4.15 mL 20.74 mL 41.48 mL
    1 mM 2.07 mL 10.37 mL 20.74 mL
    5 mM 0.41 mL 2.07 mL 4.15 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
    MAPK > MEK
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