PD98059

Catalog No.: A10705

MEK Inhibitor

PD98059 Chemical Structure

CAS NO. 167869-21-8

PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.

Availability: In stock

Package Price Qty
10 mg
$50.00
50 mg
$110.00
100 mg
$190.00
200 mg
$350.00
10mM * 1mL in DMSO
$55.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.
Targets
MEK1 (Cell-free assay)
2 μM
In vitro (25°C) DMSO 14 mg/mL heating (52.37 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 37.41 mL 187.06 mL 374.11 mL
0.5 mM 7.48 mL 37.41 mL 74.82 mL
1 mM 3.74 mL 18.71 mL 37.41 mL
5 mM 0.75 mL 3.74 mL 7.48 mL

*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10705
Actions Inhibitor
M. Wt 267.3
Formula C16H13NO3
Solubility DMSO>32mg/mL Water<1mg/mL Ethanol>3mg/mL
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 167869-21-8
Synonyms N/A
SMILES COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2

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