Total item
Cart Subtotal
$0.00 Biological Activity
PD98059 is an equipotent antagonist of the aryl hydrocarbon receptor and inhibitor of mitogen-activated protein kinase kinase.
Targets
| MEK1 (Cell-free assay) | ||||
| 2 μM |
| In vitro (25°C) | DMSO | 14 mg/mL heating (52.37 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 5 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 37.41 mL | 187.06 mL | 374.11 mL |
| 0.5 mM | 7.48 mL | 37.41 mL | 74.82 mL |
| 1 mM | 3.74 mL | 18.71 mL | 37.41 mL |
| 5 mM | 0.75 mL | 3.74 mL | 7.48 mL |
*The above data is based on the productmolecular weight 267.3. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10705 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 267.3 |
| Formula | C16H13NO3 |
| Solubility | DMSO>32mg/mL Water<1mg/mL Ethanol>3mg/mL |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 167869-21-8 |
| SMILES | COC1=CC=CC(=C1N)C2=CC(=O)C3=CC=CC=C3O2 |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
PD0325901
PD0325901 is MEK inhibitor and non-competitive with ATP, Kiapp of 1 nM against activated MEK1 and MEK2.
RO4927350
RO4927350 a potent and highly selective non-ATP-competitive MEK1/2 inhibitor.
GDC-0623
GDC-0623 is a potent and ATP-uncompetitive MEK1 inhibitor with Ki of 0.13 nM. Phase 1.
TAK-733
TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
RO4987655
RO4987655 is an orally active small molecule, targeting mitogen-activated protein kinase kinase 1 (MAP2K1 or MEK1), with potential antineopl…
GDC-0973 (Cobimetinib)
Cobimetinib (GDC-0973, RG7420) is a potent and highly selective MEK1 inhibitor with IC50 of 4.2 nM, showing more than 100-fold selectively f…
BI-847325
BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xen…
GSK1120212 (JTP-74057, Trametinib)
GSK1120212 (JTP-74057) strongly prevented the activities of MEK1 and MEK2 kinases rather than activities of other 98 kinases.
Keywords:buy PD98059 | PD98059 Supplier | purchase PD98059 | PD98059 cost | PD98059 manufacturer | order PD98059 | PD98059 distributor | buy 167869-21-8| 167869-21-8 Supplier | purchase 167869-21-8 | 167869-21-8 cost | 167869-21-8 manufacturer | order 167869-21-8 | 167869-21-8 distributor
Adooq Quality Guarantee
We promise all products perform as described.