PF-04554878 (Defactinib)

Catalog No.: A11929

FAK inhibitor

PF-04554878 (Defactinib) Chemical Structure

CAS NO. 1345713-71-4, 1073154-85-4

PF-04554878 is a novel FAK kinase inhibitor that decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells

Availability: In stock In Stock, Over Night Shipping Available

Package Price Qty
2 mg
$40.00
5 mg
$70.00
10 mg
$90.00
25 mg
$180.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-04554878 is a novel FAK kinase inhibitor that decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.95 mL 195.89 mL
0.5 mM 3.92 mL 19.59 mL 39.18 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11929
Actions Inhibitor
M. Wt 510.49
Formula C20H21F3N8O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1345713-71-4, 1073154-85-4
Synonyms PF-4554878, VS-6063
SMILES O=C(NC)C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=NC=CN=C3N(C)S(=O)(C)=O)=N2)C=C1

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