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PF-04554878 (Defactinib)


FAK inhibitor

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Catalog No. A11929

Availability:Stock in USAIn stock In Stock, Over Night Shipping Available

Product Name Catalog No. Price Qty
PF-04554878 2mg A11929-2

Regular Price: $40.00

Special Price: $36.00

PF-04554878 5mg A11929-5

Regular Price: $70.00

Special Price: $63.00

PF-04554878 10mg A11929-10

Regular Price: $90.00

Special Price: $81.00

PF-04554878 25mg A11929-25

Regular Price: $180.00

Special Price: $162.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PF-04554878 is a novel FAK kinase inhibitor that decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells

PF-04554878 (Defactinib)

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Publications citing Adooq Products
PF-04554878 (Defactinib) Citations (1)
  • Shalana O'Brien, .et al. FAK inhibition with small molecule inhibitor Y15 decreases viability, clonogenicity, and cell attachment in thyroid cancer cell lines and synergizes with targeted therapeutics, Oncotarget., 2014, Sep; 5(17): 7945-7959. PMID: 25277206

Chemical Information

Catalog Num A11929
Actions Inhibitor
M. Wt 510.49
Formula C20H21F3N8O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1345713-71-4, 1073154-85-4
Synonyms PF-4554878, VS-6063

Biological Activity

PF-04554878 is a novel FAK kinase inhibitor that decreases growth and induces apoptosis in pancreatic neuroendocrine tumor cells

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.59 mL 97.95 mL 195.89mL
0.5 mM 3.92 mL 19.59 mL 39.18 mL
1 mM 1.96 mL 9.79 mL 19.59 mL
5 mM 0.39 mL 1.96 mL 3.92 mL

*The above data is based on the productmolecular weight 510.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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