PF-04620110

Catalog No.: A11526

DGAT1 Inhibitor

PF-04620110

PF-04620110 Chemical Structure

CAS NO. 1109276-89-2

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.

Availability: In stock

Package Price Qty
10 mg
$96.00
25 mg
$220.00
50 mg
$350.00
10mM * 1mL in DMSO
$99.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF-04620110 is an orally active, selective and potent diglyceride acyltransferase-1 (DGAT1) inhibitor with IC50 of 19 nM.
Targets
DGAT1
19 nM
In vitro DMSO 49 mg/mL heating (123.6 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.22 mL 126.12 mL 252.24 mL
0.5 mM 5.04 mL 25.22 mL 50.45 mL
1 mM 2.52 mL 12.61 mL 25.22 mL
5 mM 0.5 mL 2.52 mL 5.04 mL

*The above data is based on the productmolecular weight 396.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11526
Actions Inhibitor
M. Wt 396.44
Formula C21H24N4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1109276-89-2
Synonyms PF04620110
SMILES C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)N3CCOC4=NC=NC(=C4C3=O)N

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