PF 431396

Catalog No.: A11142

FAK/PYK2 inhibitor

PF 431396

PF 431396 Chemical Structure

CAS NO. 717906-29-1

PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively).

Availability: In stock

Package Price Qty
10 mg

Regular Price: $80.00

Special Price $72.00

25 mg

Regular Price: $160.00

Special Price $144.00

50 mg

Regular Price: $280.00

Special Price $252.00

100 mg

Regular Price: $480.00

Special Price $432.00

10mM * 1mL in DMSO

Regular Price: $105.00

Special Price $94.50

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PF 431396 is a dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor (IC50 values are 2 and 11 nM respectively).
Targets
FAK PYK2
2 nM11 nM
In vitro DMSO 100 mg/mL (197.43 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.74 mL 98.72 mL 197.43 mL
0.5 mM 3.95 mL 19.74 mL 39.49 mL
1 mM 1.97 mL 9.87 mL 19.74 mL
5 mM 0.39 mL 1.97 mL 3.95 mL

*The above data is based on the productmolecular weight 506.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11142
Actions Inhibitor
M. Wt 506.5
Formula C22H21F3N6O3S
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 717906-29-1
Synonyms PF-431396
SMILES CN(C1=CC=CC=C1CNC2=NC(=NC=C2C(F)(F)F)NC3=CC4=C(C=C3)NC(=O)C4)S(=O)(=O)C

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