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CDK Inhibitor

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Catalog No. A10716

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
PHA-793887 5mg A10716-5

Regular Price: $90.00

Special Price: $81.00

PHA-793887 10mg A10716-10

Regular Price: $150.00

Special Price: $135.00

PHA-793887 50mg A10716-50

Regular Price: $450.00

Special Price: $405.00

PHA-793887 100mg A10716-100

Regular Price: $750.00

Special Price: $675.00

PHA-793887 10mM * 1mL in DMSO A10716-10mM-D

Regular Price: $110.00

Special Price: $99.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity against several cancer cell lines.


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Publications citing Adooq Products
PHA-793887 Citations (1)
  • Hirosumi Tamura, .et al. Evaluation of anticancer agents using patient-derived tumor organoids characteristically similar to source tissues, Oncol Rep, 2018, Aug; 40(2): 635-646 PMID: 29917168

Chemical Information

Catalog Num A10716
Actions Inhibitor
M. Wt 361.5
Formula C19H31N5O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 718630-59-2
Synonyms PHA793887

Biological Activity

PHA-793887, a novel potent inhibitor of Cdk, target on kinds of cyclin-dependent kinase under low concentrations and poses high activity against several cancer cell lines.
Target Value
CDK5/p25IC50: 5nM
CDK2/CyclinAIC50: 8nM
CDK2/CyclinEIC50: 8nM
CDK7/CyclinHIC50: 10nM
CDK1/CyclinBIC50: 60nM
CDK4/CyclinD1IC50: 62nM
GSK-3βIC50: 79nM
CDK9/CyclinT1IC50: 138nM


Solubility (25°C) * In vitro DMSO 72 mg/mL (199.18 mM)
Water <1 mg/mL (<1 mM)
Ethanol 72 mg/mL (199.18 mM)
In vivo 30% propylene glycol, 5% Tween 80, 65% D5W 15 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.66 mL 138.31 mL 276.63mL
0.5 mM 5.53 mL 27.66 mL 55.33 mL
1 mM 2.77 mL 13.83 mL 27.66 mL
5 mM 0.55 mL 2.77 mL 5.53 mL

*The above data is based on the productmolecular weight 361.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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