PI3K/Akt/mTOR

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  1. benzodiazepine1 (BZ1) receptor agonist

    SX-3228 is a selective benzodiazepine1 (BZ1) receptor agonist with an IC50 of 17 nM.
  2. NMDA receptor partial agonist

    Apimostinel (NRX-1074; AGN-241660) is an orally active NMDA receptor partial agonist.
  3. GABAA α2/α3 agonist

    TPA 023 is a GABAA α2/α3 subtype-selective agonist, with Ki of 0.19-0.41 nM.

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