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- Pridham KJ,et al. PIK3CB/p110汕 is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 29016844
|Storage||at -20°C 3 years Powder|
|Chemical Name||2-methyl-5-nitro-2-[(6-bromoimidazo[1,2-a]pyridin-3-yl)methylene]-1-methylhydrazide-benzenesulfonic acid|
|PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 µM and 1.3 µM, respectively.|
|Solubility (25°C)*||In vitro||DMSO||3 mg/mL (6.13 mM)|
|Water||<1 mg/mL (<1 mM)|
|Ethanol||<1 mg/mL (<1 mM)|
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
|Concentration / Solvent Volume / Mass||1 mg||5 mg||10 mg|
|0.1 mM||20.46 mL||102.31 mL||204.62mL|
|0.5 mM||4.09 mL||20.46 mL||40.92 mL|
|1 mM||2.05 mL||10.23 mL||20.46 mL|
|5 mM||0.41 mL||2.05 mL||4.09 mL|
*The above data is based on the productmolecular weight 488.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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