PIK-75

Catalog No.: A10729

PI3K Inhibitor

PIK-75

PIK-75 Chemical Structure

CAS NO. 372196-77-5

PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 µM and 1.3 µM, respectively.

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$70.00
50 mg
$120.00
100 mg
$170.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PIK-75 is an imidazopyridine that selectively inhibits p110α with an IC50 value of 5.8 nM.2 It inhibits p110γ and p110β considerably less effectively with IC50 values of 0.076 µM and 1.3 µM, respectively.
Targets
DNA-PK (Cell-free assay) p110α (Cell-free assay) p110γ (Cell-free assay) p110δ (Cell-free assay) p110β (Cell-free assay)
2 nM5.8 nM76 nM0.51 μM1.3 μM
In vitro DMSO 3 mg/mL (6.13 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 20.46 mL 102.31 mL 204.62 mL
0.5 mM 4.09 mL 20.46 mL 40.92 mL
1 mM 2.05 mL 10.23 mL 20.46 mL
5 mM 0.41 mL 2.05 mL 4.09 mL

*The above data is based on the productmolecular weight 488.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A10729
Actions Inhibitor
M. Wt 488.7
Formula C16H14BrN5O4S.HCl
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 372196-77-5
Synonyms PIK75
SMILES CC1=C(C=C(C=C1)[N+](=O)[O-])S(=O)(=O)N(C)/N=C/C2=CN=C3N2C=C(C=C3)Br.Cl

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy PIK-75 | PIK-75 Supplier | purchase PIK-75 | PIK-75 cost | PIK-75 manufacturer | order PIK-75 | PIK-75 distributor | buy 372196-77-5| 372196-77-5 Supplier | purchase 372196-77-5 | 372196-77-5 cost | 372196-77-5 manufacturer | order 372196-77-5 | 372196-77-5 distributor
Rewards