Pimecrolimus

Catalog No.: A10732

Pimecrolimus

Pimecrolimus Chemical Structure

CAS NO. 137071-32-0

Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).

Availability: In stock

Package Price Qty
25 mg
$40.00
50 mg
$72.00
100 mg
$130.00
10mM * 1mL in DMSO
$55.00
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Biological Activity

Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).
Targets
In vitro DMSO 100 mg/mL (123.38 mM)
Water <1 mg/mL (<1 mM)
Ethanol 100 mg/mL (123.38 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 12.34 mL 61.69 mL 123.38 mL
0.5 mM 2.47 mL 12.34 mL 24.68 mL
1 mM 1.23 mL 6.17 mL 12.34 mL
5 mM 0.25 mL 1.23 mL 2.47 mL

*The above data is based on the productmolecular weight 810.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10732
M. Wt 810.5
Formula C43H68ClNO11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 137071-32-0
Synonyms Elidel, SDZ-ASM-981
SMILES CC[[email protected]@H]1/C=C(\C[[email protected]@H](C[[email protected]@H]([[email protected]@H]2[[email protected]](C[[email protected]]([[email protected]@](O2)(C(=O)C(=O)N3CCCC[[email protected]]3C(=O)O[[email protected]@H]([[email protected]@H]([[email protected]](CC1=O)O)C)/C(=C/[[email protected]@H]4CC[[email protected]@H]([[email protected]@H](C4)OC)Cl)/C)O)C)OC)OC)C)/C

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