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$0.00 Biological Activity
Pimecrolimus is a natural ascomycin macrolactam that binds to macrophilin-12 (FKBP-12) and inhibits calcineurin as well as prolyl isomerase (rotamase).
Targets
| In vitro | DMSO | 94 mg/mL (115.98 mM) | |
| Water | Insoluble | ||
| Ethanol | 94 mg/mL (115.98 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.34 mL | 61.69 mL | 123.38 mL |
| 0.5 mM | 2.47 mL | 12.34 mL | 24.68 mL |
| 1 mM | 1.23 mL | 6.17 mL | 12.34 mL |
| 5 mM | 0.25 mL | 1.23 mL | 2.47 mL |
*The above data is based on the productmolecular weight 810.5 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10732 |
|---|---|
| CAS No. | 137071-32-0 |
| Formula | C43H68ClNO11 |
| M. Wt | 810.5 |
| Purity | >98% |
| Synonyms | Elidel, SDZ-ASM-981 |
| SMILES | CC[[email protected]@H]1/C=C(\C[[email protected]@H](C[[email protected]@H]([[email protected]@H]2[[email protected]](C[[email protected]]([[email protected]@](O2)(C(=O)C(=O)N3CCCC[[email protected]]3C(=O)O[[email protected]@H]([[email protected]@H]([[email protected]](CC1=O)O)C)/C(=C/[[email protected]@H]4CC[[email protected]@H]([[email protected]@H](C4)OC)Cl)/C)O)C)OC)OC)C)/C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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