Biological Activity
PKI-402 is a dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor.
In vitro (25°C) | DMSO | 0.4 mg/mL (<1 mM) | |
Water | <1 mg/mL (<1 mM) | ||
Ethanol | <1 mg/mL (<1 mM) | ||
In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.52 mL | 87.61 mL | 175.22 mL |
0.5 mM | 3.5 mL | 17.52 mL | 35.04 mL |
1 mM | 1.75 mL | 8.76 mL | 17.52 mL |
5 mM | 0.35 mL | 1.75 mL | 3.5 mL |
*The above data is based on the productmolecular weight 570.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A11089 |
---|---|
Actions | Inhibitor |
M. Wt | 570.7 |
Formula | C29H34N10O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1173204-81-3 |
Synonyms | PKI402 |
SMILES | CCN1C2=C(C(=NC(=N2)C3=CC=C(C=C3)NC(=O)NC4=CC=C(C=C4)C(=O)N5CCN(CC5)C)N6CCOCC6)N=N1 |
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