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PLX4032 (Vemurafenib)
Catalog No.: A10739
Raf inhibitor
PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.
Adooq Products cited in reputable paper
Adooq's PLX4032 (Vemurafenib) has been cited by 12 publications
Vijaya Bharti, .et al. , Cell Rep , 2022, Dec 20;41(12):111826 PMID: 36543138 Lee YJ, .et al. , Research Square , 2022, April 27th Aya Hasan Alshammari, .et al. , Biochem Pharmacol , 2022, Mar;197:114914 PMID: 35041812 Guixin Zhu, .et al. , Nat Cell Biol , 2021, Sep;23(9):978-991 PMID: 34497368 Makoto Koyama, .et al. , Int J Oncol , 2020, Sep 2 PMID: 32901840 Kudo K, .et al. , FASEB J , 2018, Dec 3:fj201800664RR PMID: 30508500 Min Ho Choe, .et al. , Cell Death Dis , 2018, Jun; 9(6): 640 PMID: 29844307 Jan Dorrie, .et al. , Int J Mol Sci , 2018, Jan; 19(1): 289 PMID: 29346301 Aishwarya Kundu, .et al. , Mol Carcinog , 2017, Jan; 56(1): 49-61 PMID: 26878440 Fujita KI, .et al. , J Pharm Sci , 2017, Sep;106(9):2632-2641 PMID: 28479358 Toshinori Sueda, .et al. , Sci Rep , 2016, 6: 18949 PMID: 26750638 Yanling Li, .et al. , Onco Targets Ther , 2015, 8: 1043-1051 PMID: 25999739
Biological Activity
Discription
PLX4032 (Vemurafenib) also known as RG7204, Vemurafenib, R7204; RO5185426. PLX4032 is a B-raf inhibitor with an IC50 of 44 nM.
Targets
Solubility
In vitro (25°C)
DMSO
83 mg/mL (169.41 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
4% DMSO+30% PEG 300+5% Tween 80+ddH2O (suspension)
4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass
1 mg
5 mg
10 mg
0.1 mM
20.41 mL
102.06 mL
204.12 mL
0.5 mM
4.08 mL
20.41 mL
40.82 mL
1 mM
2.04 mL
10.21 mL
20.41 mL
5 mM
0.41 mL
2.04 mL
4.08 mL
Useful Calculator
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)
* Please check COA/MSDS for correct molecular weight.
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1 V1 = C2 V2
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