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PQ 401

Catalog No.: A11951
IGF-1R inhibitor
PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.
PQ 401
Grouped product items
Product Name Price Stock Qty
PQ 401 10mg
Special Price $72.00 Regular Price $90.00
In stock
PQ 401 25mg
Special Price $144.00 Regular Price $180.00
In stock
PQ 401 50mg
Special Price $232.00 Regular Price $290.00
In stock
PQ 401 100mg
Special Price $440.00 Regular Price $550.00
In stock
PQ 401 10mM * 1mL in DMSO
Special Price $72.00 Regular Price $90.00
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.
Targets
Target Value
Product Information
Catalog Num A11951
Formula C18H16ClN3O2
Molecular Weight 341.79
CAS Number 196868-63-0
SMILES CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC
Synonyms PQ401
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Solubility
In vitro (25°C) DMSO 30 mg/mL (87.77 mM)
Water Insoluble
Ethanol Insoluble
In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.26 mL 146.29 mL 292.58 mL
0.5 mM 5.85 mL 29.26 mL 58.52 mL
1 mM 2.93 mL 14.63 mL 29.26 mL
5 mM 0.59 mL 2.93 mL 5.85 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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Protein Tyrosine Kinases > IGF-1R
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