PQ 401

Name: PQ 401
Brand: Adooq Bioscience
SKU: A11951
Rating: 100 (268 reviews)

Catalog No.: A11951

IGF-1R inhibitor

PQ 401 Chemical Structure

CAS NO. 196868-63-0

PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.

Availability: In stock

Package	Price	Qty
10 mg	$90.00
25 mg	$180.00
50 mg	$290.00
100 mg	$550.00
10mM * 1mL in DMSO	$90.00
Custom Size	Get quote

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Products are for laboratory research use only. Not for human use. We do not sell to patients.

Adooq Products cited in reputable paper

Biological Activity

PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.

Targets

IGF-1R
<1 μM

Solubility *

In vitro (25°C)	DMSO	30 mg/mL (87.77 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	29.26 mL	146.29 mL	292.58 mL
0.5 mM	5.85 mL	29.26 mL	58.52 mL
1 mM	2.93 mL	14.63 mL	29.26 mL
5 mM	0.59 mL	2.93 mL	5.85 mL

*The above data is based on the productmolecular weight 341.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num	A11951
Actions	Inhibitor
CAS No.	196868-63-0
Formula	C18H16ClN3O2
M. Wt	341.79
Purity	>98%
Synonyms	PQ401
SMILES	CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.