PQ 401

Catalog No.: A11951

IGF-1R inhibitor

PQ 401

PQ 401 Chemical Structure

CAS NO. 196868-63-0

PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.

Availability: In stock

Package Price Qty
10 mg
$90.00
25 mg
$180.00
50 mg
$290.00
100 mg
$550.00
10mM * 1mL in DMSO
$90.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.
Targets
IGF-1R
<1 μM
In vitro (25°C) DMSO 32 mg/mL (93.62 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 5 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.26 mL 146.29 mL 292.58 mL
0.5 mM 5.85 mL 29.26 mL 58.52 mL
1 mM 2.93 mL 14.63 mL 29.26 mL
5 mM 0.59 mL 2.93 mL 5.85 mL

*The above data is based on the productmolecular weight 341.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Chemical Properties

Catalog Num A11951
Actions Inhibitor
M. Wt 341.79
Formula C18H16ClN3O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 196868-63-0
Synonyms PQ401
SMILES CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC

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