Total item
Cart Subtotal
$0.00 Biological Activity
PQ 401 is a cell-permeable phenylquinolinyl-urea compound that inhibits IGF-1R autophosphorylation.
Targets
| IGF-1R | ||||
| <1 μM |
| In vitro (25°C) | DMSO | 32 mg/mL (93.62 mM) | |
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 5 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.26 mL | 146.29 mL | 292.58 mL |
| 0.5 mM | 5.85 mL | 29.26 mL | 58.52 mL |
| 1 mM | 2.93 mL | 14.63 mL | 29.26 mL |
| 5 mM | 0.59 mL | 2.93 mL | 5.85 mL |
*The above data is based on the productmolecular weight 341.79. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11951 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 341.79 |
| Formula | C18H16ClN3O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 196868-63-0 |
| Synonyms | PQ401 |
| SMILES | CC1=NC2=CC=CC=C2C(=C1)NC(=O)NC3=C(C=CC(=C3)Cl)OC |
Product Tags
Product Questions
Product Questions
No Questions
You may also be interested in the following product(s)
NVP-AEW541
NVP-AEW541 is a selective IGF-1R kinase inhibitor that inhibits the autophosphorylation activity of IGF-1R (IC50 = 0.086 uM) and prevents IG…
Picropodophyllin
Picropodophyllin (AXL1717) is the first targeted oral small-molecule IGF-1 receptor inhibitor with no effect on the insulin receptor.
AG-1024 (Tyrphostin)
AG-1024 (Tyrphostin) is a specific inhibitor of insulin-like growth factor-1 (IGF-1) and insulin receptor tyrosine kinase activity. Exhibits…
BMS-754807
BMS-754807 is an efficacious, orally active growth factor 1 receptor/insulin receptor family-targeted kinase inhibitor that may act in combi…
OSI-906
OSI-906 is a potential first-in-class selective small molecule, dual kinase inhibitor of both insulin-like growth factor-1 receptor (IGF-1R)…
XL-228
XL228 is a protein kinase inhibitor targeting IGF1R, the AURORA kinases, FGFR1-3, ABL and SRC family kinases. XL228 is an Aurora A inhibitor…
NVP-ADW742
NVP-ADW742 is an IGF-1R inhibitor with IC50 of 0.17 μM.
GSK1904529A
GSK1904529A selectively inhibits IGF-IR and IR with IC(50)s of 27 and 25 nmol/L, respectively.
Keywords:buy PQ 401 | PQ 401 Supplier | purchase | cost | manufacturer | order | distributor | buy 196868-63-0| 196868-63-0 Supplier | purchase 196868-63-0 | 196868-63-0 cost | 196868-63-0 manufacturer | order 196868-63-0 | 196868-63-0 distributor
Contact information
United StatesAdooq Bioscience
Toll Free: (866) 930-6790
Fax: +1-323-606-8156
Email: [email protected]
Not your Region? View all Distributors
Adooq Quality Guarantee
We promise all products perform as described.