Pregnane X Receptors

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  1. Meclizine 2HCl

    Catalog No. A11700
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    Meclizine is a human pregnane X receptor (hPXR) agonist. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. Learn More
  2. Pregnenolone

    Catalog No. A11909
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    Pregnenolone is an endogenous steroid hormone for inhibition of M1 receptor- and M3 receptor-mediated currents with IC50 of 11.4 μM and 6.0 μM, respectively. Learn More
  3. Rifampin

    Catalog No. A10791
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    RNA polymerase inhibitor
    Antibiotic; inhibits bacterial RNA polymerase. Prototypical activator of the pregnane X receptor (PXR). Learn More
  4. SR-12813

    Catalog No. A16125
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    PXR agonist
    SR-12813 is a pregnane X receptor (PXR) agonist. Learn More

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