Purvalanol B

Catalog No.: A12352

CDK inhibitor

Purvalanol B Chemical Structure

CAS NO. 212844-54-7

Purvalanol B is a cyclin-dependent kinase inhibitor. IC50 values are 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Selective over a range of other protein kinases (IC50 > 10,000 nM).

Availability: In stock

Package Price Qty
10 mg
$120.00
25 mg
$250.00
50 mg
$450.00
100 mg
$850.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Purvalanol B is a cyclin-dependent kinase inhibitor. IC50 values are 6, 6, 9, > 10,000, and 6 nM for cdc2/cyclin B, cdk2/cyclin A, cdk2/cyclin E, cdk4/cyclin D1 and cdk5-p35 respectively. Selective over a range of other protein kinases (IC50 > 10,000 nM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.1 mL 115.5 mL 230.99 mL
0.5 mM 4.62 mL 23.1 mL 46.2 mL
1 mM 2.31 mL 11.55 mL 23.1 mL
5 mM 0.46 mL 2.31 mL 4.62 mL

*The above data is based on the productmolecular weight 432.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12352
Actions Inhibitor
M. Wt 432.91
Formula C20H25ClN6O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 212844-54-7
Synonyms NG 95
SMILES CC(C)[[email protected]](CO)NC1=NC2=C(C(=N1)NC3=CC(=C(C=C3)C(=O)O)Cl)N=CN2C(C)C

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