Reboxetine mesylate

Reboxetine is an antidepressant compound that selectively inhibits norepinephrine uptake (IC50s = 8.2 and 1,070 nM for norepinephrine and serotonin transporters, respectively). It displays greater than 1,000-fold affinity for binding rat norepinephrine receptors compared to serotonin, histamine, acetylcholine, or dopamine receptors (Kis = 1.1, 129, 1,400, 3,900, and >10,000 nM, respectively).
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Size Price Stock Qty
5mg
$35.00
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10mg
$65.00
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25mg
$155.00
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50mg
$300.00
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100mg
$480.00
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500mg
$1,055.00
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10mM * 1mL in DMSO
$35.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Reboxetine mesylate has been cited by 1 publications
  • Antonia Donat, .et al. , iScience, 2023, Aug 29;26(10):107761 PMID: 37720081
  • Biological Activity
    Discription Reboxetine is an antidepressant compound that selectively inhibits norepinephrine uptake (IC50s = 8.2 and 1,070 nM for norepinephrine and serotonin transporters, respectively). It displays greater than 1,000-fold affinity for binding rat norepinephrine receptors compared to serotonin, histamine, acetylcholine, or dopamine receptors (Kis = 1.1, 129, 1,400, 3,900, and >10,000 nM, respectively).
    Targets
    Target Value
    Product Information
    Catalog Num A11919
    Formula C19H23NO3.CH4SO3
    Molecular Weight 409.5
    CAS Number 98769-84-7
    SMILES CCOC1=CC=CC=C1O[C@@H]([C@H]2CNCCO2)C3=CC=CC=C3.CS(=O)(=O)O
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro DMSO 81 mg/mL (197.8 mM)
    Water 81 mg/mL (197.8 mM)
    Ethanol Insoluble
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.42 mL 122.1 mL 244.2 mL
    0.5 mM 4.88 mL 24.42 mL 48.84 mL
    1 mM 2.44 mL 12.21 mL 24.42 mL
    5 mM 0.49 mL 2.44 mL 4.88 mL
    Useful Calculator

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    This equation is commonly abbreviated as: C1V1 = C2V2

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