Refametinib (RDEA-119, BAY 86-9766)

Refametinib (RDEA-119, BAY 86-9766) Chemical Structure

CAS NO. 923032-38-6

Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity.

Availability: In stock

Package Price Qty
10 mg

Regular Price: $214.00

Special Price $171.20

25 mg

Regular Price: $290.00

Special Price $232.00

50 mg

Regular Price: $599.00

Special Price $479.20

100 mg

Regular Price: $1,026.00

Special Price $820.80

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Biological Activity

Refametinib, also known as RDEA119, BAY 86-9766, is an orally bioavailable selective MEK inhibitor with potential antineoplastic activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.47 mL 87.36 mL 174.72 mL
0.5 mM 3.49 mL 17.47 mL 34.94 mL
1 mM 1.75 mL 8.74 mL 17.47 mL
5 mM 0.35 mL 1.75 mL 3.49 mL

*The above data is based on the productmolecular weight 572.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12866
Actions Inhibitor
CAS No. 923032-38-6
Formula C19H20F3IN2O5S
M. Wt 572.34
Purity >98%
Synonyms RDEA119, RDEA 119, BAY 86-9766, BAY 869766, BAY869766
SMILES COC1=CC(=C(C(=C1NS(=O)(=O)C2(CC2)C[[email protected]](CO)O)NC3=C(C=C(C=C3)I)F)F)F
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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