RKI-1447
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | RKI-1447 is a potent inhibitor of the Rho-associated ROCK kinases with anti-invasive and antitumor activities in breast cancer. | ||
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Targets |
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Catalog Num | A13067 |
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Formula | C16H14N4O2S |
Molecular Weight | 326.37 |
CAS Number | 1342278-01-6 |
SMILES | C1=CC(=CC(=C1)O)CNC(=O)NC2=NC(=CS2)C3=CC=NC=C3 |
Synonyms | RKI1447; RKI 1447. ROCK Inhibitor XIII |
Storage | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | 62 mg/mL (189.97 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 15% Captisol | 28 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 30.64 mL | 153.2 mL | 306.4 mL |
0.5 mM | 6.13 mL | 30.64 mL | 61.28 mL |
1 mM | 3.06 mL | 15.32 mL | 30.64 mL |
5 mM | 0.61 mL | 3.06 mL | 6.13 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2