RO3280

Catalog No.: A13245
PLK1 inhibitor
RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
Grouped product items
Product Name Price Stock Qty
RO3280 5mg
Special Price $96.00 Regular Price $120.00
In stock
RO3280 10mg
Special Price $160.00 Regular Price $200.00
In stock
RO3280 25mg
Special Price $320.00 Regular Price $400.00
In stock
RO3280 50mg
Special Price $560.00 Regular Price $700.00
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RO3280 10mM * 1mL in DMSO
Special Price $151.20 Regular Price $189.00
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Biological Activity
Discription RO3280 is a potent, highly selective inhibitor of Polo-like kinase 1 (PLK1) with IC50 of 3 nM.
Targets
Target Value
Product Information
Catalog Num A13245
Formula C27H35F2N7O3
Molecular Weight 543.61
CAS Number 1062243-51-9
SMILES CN1CCC(CC1)NC(=O)C2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(CC(C(=O)N4C)(F)F)C5CCCC5)OC
Synonyms RO 3280, RO-3280
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility
In vitro DMSO 87 mg/mL (160.04 mM)
Water Insoluble
Ethanol 87 mg/mL (160.04 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 18.4 mL 91.98 mL 183.96 mL
0.5 mM 3.68 mL 18.4 mL 36.79 mL
1 mM 1.84 mL 9.2 mL 18.4 mL
5 mM 0.37 mL 1.84 mL 3.68 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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