Roflumilast

Catalog No.: A10804

PDE inhibitor

Roflumilast

Roflumilast Chemical Structure

CAS NO. 162401-32-3

Roflumilast acts as a selective, long-acting inhibitor of the enzyme PDE-4.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $55.00

Special Price $49.50

10 mg

Regular Price: $90.00

Special Price $81.00

50 mg

Regular Price: $180.00

Special Price $162.00

100 mg

Regular Price: $320.00

Special Price $288.00

10mM * 1mL in DMSO

Regular Price: $103.00

Special Price $92.70

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Roflumilast acts as a selective, long-acting inhibitor of the enzyme PDE-4.
Targets
Target Value
PDE4B2IC50: 0.2nM
PDE4A1IC50: 0.7nM
PDE4B1IC50: 0.7nM
PDE4A4IC50: 0.9nM
PDE4C1IC50: 3nM
PDE4C2IC50: 4.3nM
In vitro (25°C) DMSO 81 mg/mL (200.88 mM)
Water <1 mg/mL (<1 mM)
Ethanol 15 mg/mL (37.2 mM)
In vivo 30% PEG400/0.5% Tween80/5% propylene glycol 30 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.8 mL 124.01 mL 248.02 mL
0.5 mM 4.96 mL 24.8 mL 49.6 mL
1 mM 2.48 mL 12.4 mL 24.8 mL
5 mM 0.5 mL 2.48 mL 4.96 mL

*The above data is based on the productmolecular weight 403.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10804
Actions Inhibitor
M. Wt 403.2
Formula C17H14Cl2F2N2O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 162401-32-3
Synonyms Daxas, Daliresp
SMILES C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F

Product Tags

Product Tags

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Roflumilast | Roflumilast Supplier | purchase Roflumilast | Roflumilast cost | Roflumilast manufacturer | order Roflumilast | Roflumilast distributor | buy 162401-32-3| 162401-32-3 Supplier | purchase 162401-32-3 | 162401-32-3 cost | 162401-32-3 manufacturer | order 162401-32-3 | 162401-32-3 distributor
Rewards