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Roflumilast

Catalog No.: A10804
PDE inhibitor
Adooq's Roflumilast has been cited by 3 publications
Roflumilast acts as a selective, long-acting inhibitor of the enzyme PDE-4.
Roflumilast
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Size Price Stock Qty
5mg
$35.00
In stock
10mg
$60.00
In stock
50mg
$175.00
In stock
100mg
$255.00
In stock
10mM * 1mL in DMSO
$45.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's Roflumilast has been cited by 3 publications
  • Bo Liao, .et al. , Exp Ther Med, 2023, May 9;25(6):302 PMID: 37229319
  • Zhongyuan Zhang, .et al. , Exp Ther Med, 2021, Dec;22(6):1398 PMID: 34650646
  • Bing Zhong, .et al. , ACS Omega, 2021, Jan 26; 6(3): 2149-2155 PMID: 33521454
    • Biological Activity
    Discription Roflumilast acts as a selective, long-acting inhibitor of the enzyme PDE-4.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10804
    Formula C17H14Cl2F2N2O3
    Molecular Weight 403.2
    CAS Number 162401-32-3
    SMILES C1CC1COC2=C(C=CC(=C2)C(=O)NC3=C(C=NC=C3Cl)Cl)OC(F)F
    Synonyms Daxas, Daliresp
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 70 mg/mL (173.6 mM)
    Water Insoluble
    Ethanol 13 mg/mL (32.24 mM)
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 24.8 mL 124.01 mL 248.02 mL
    0.5 mM 4.96 mL 24.8 mL 49.6 mL
    1 mM 2.48 mL 12.4 mL 24.8 mL
    5 mM 0.5 mL 2.48 mL 4.96 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

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      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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    Metabolism > PDE
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