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SAR131675

Catalog No.: A13377

VEGFR3 Inhibitor

SAR131675

SAR131675 Chemical Structure

CAS NO. 1433953-83-3

SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities.

Availability: In stock

Package Price Qty
10 mg
$142.00
25 mg
$284.00
50 mg
$426.00
100 mg
$710.00
10mM * 1mL in DMSO
$80.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities.
Targets
VEGFR3 (Cell-free assay)
23 nM
In vitro (25°C) DMSO 29 mg/mL (80.91 mM)
Water Insoluble
Ethanol Insoluble
In vivo 5% DMSO+30% PEG 300+5% Tween 80+ddH2O 2 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 27.91 mL 139.55 mL 279.1 mL
0.5 mM 5.58 mL 27.91 mL 55.82 mL
1 mM 2.79 mL 13.96 mL 27.91 mL
5 mM 0.56 mL 2.79 mL 5.58 mL

*The above data is based on the productmolecular weight 358.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13377
Actions Inhibitor
CAS No. 1433953-83-3
Formula C18H22N4O4
M. Wt 358.29
Purity >98%
Synonyms 0
SMILES CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[[email protected]](C)(COC)O)C(=O)NC)N
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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