SL 0101-1

Catalog No.: A11160

RSK Inhibitor

SL 0101-1

SL 0101-1 Chemical Structure

CAS NO. 77307-50-7

SL 0101-1 is a selective inhibitor of p90 ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2). It also inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.

Availability: Out of stock

Package Price
10 mg
$140.00
25 mg
$300.00
50 mg
$560.00
100 mg
$950.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Pirbhoy PS, .et al. Synaptically driven phosphorylation of ribosomal protein S6 is differentially regulated at active synapses versus dendrites and cell bodies by MAPK and PI3K/mTOR signaling pathways, Learn Mem, 2017, Aug; 24(8): 341-357 PMID: 28716954

Biological Activity

SL 0101-1 is a selective inhibitor of p90 ribosomal S6 kinase (RSK) (IC50 = 89 nM for RSK2). It also inhibits the growth of MCF-7 human breast cancer cells with no effect on the normal breast cell line.

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.36 mL 96.81 mL 193.63 mL
0.5 mM 3.87 mL 19.36 mL 38.73 mL
1 mM 1.94 mL 9.68 mL 19.36 mL
5 mM 0.39 mL 1.94 mL 3.87 mL

*The above data is based on the productmolecular weight 516.45. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A11160
Actions Inhibitor
CAS No. 77307-50-7
Formula C25H24O12
M. Wt 516.45
Purity >98%
Synonyms SL0101-1
SMILES C[[email protected]]1[[email protected]@H]([[email protected]]([[email protected]]([[email protected]@H](O1)OC2=C(OC3=CC(=CC(=C3C2=O)O)O)C4=CC=C(C=C4)O)O)OC(=O)C)OC(=O)C
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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