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MEK Inhibitor

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Catalog No. A11040

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
TAK-733 5mg A11040-5

Regular Price: $90.00

Special Price: $81.00

TAK-733 10mg A11040-10

Regular Price: $160.00

Special Price: $144.00

TAK-733 50mg A11040-50

Regular Price: $450.00

Special Price: $405.00

TAK-733 100mg A11040-100

Regular Price: $750.00

Special Price: $675.00

TAK-733 10mM * 1mL in DMSO A11040-10mM-D

Regular Price: $120.00

Special Price: $108.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.


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Chemical Information

Catalog Num A11040
Actions Inhibitor
M. Wt 504.2
Formula C17H15F2IN4O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1035555-63-5
Synonyms TAK733
SMILES CN1C2=C(C(=C(C1=O)F)NC3=C(C=C(C=C3)I)F)C(=O)N(C=N2)C[[email protected]](CO)O

Biological Activity

TAK-733 is an orally bioavailable small-molecule inhibitor of MEK1 and MEK2 (MEK1/2) with potential antineoplastic activity.
3.2 nM


Solubility (25°C)* In vitro DMSO 101 mg/mL (200.3 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 19.83 mL 99.17 mL 198.33mL
0.5 mM 3.97 mL 19.83 mL 39.67 mL
1 mM 1.98 mL 9.92 mL 19.83 mL
5 mM 0.4 mL 1.98 mL 3.97 mL

*The above data is based on the productmolecular weight 504.2 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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