Talnetant hydrochloride

Catalog No.: A15255

NK3 receptor antagonist

Talnetant hydrochloride Chemical Structure

CAS NO. 204519-66-4

Talnetant Hcl is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.

Availability: In stock

Package Price Qty
10 mg
$128.00
25 mg
$280.00
50 mg
$500.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Talnetant Hcl is a potent and selective NK3 receptor antagonist(ki=1.4 nM, hNK-3-CHO); 100-fold selective for the hNK-3 versus hNK-2 receptor, with no affinity for the hNK-1 at concentrations up to 100 uM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.87 mL 119.35 mL 238.71 mL
0.5 mM 4.77 mL 23.87 mL 47.74 mL
1 mM 2.39 mL 11.94 mL 23.87 mL
5 mM 0.48 mL 2.39 mL 4.77 mL

*The above data is based on the productmolecular weight 418.92. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A15255
Actions Antagonist
M. Wt 418.92
Formula C25H23ClN2O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 204519-66-4
Synonyms SB-223412 hydrochloride, SB223412 hydrochloride, SB 223412 hydrochloride, SB 223412-A
SMILES CCC(C1=CC=CC=C1)NC(=O)C2=C(C(=NC3=CC=CC=C32)C4=CC=CC=C4)O.Cl

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