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$0.00 - Hannah Cetuk, .et al. Partitioning of Seven Different Classes of Antibiotics into LPS Monolayers Supports Three Different Permeation Mechanisms through the Outer Bacterial Membrane, Langmuir, 2021, Feb 2;37(4):1372-1385 PMID: 33449700
Biological Activity
Telithromycin is a ketolide antibiotic. It is used to treat community acquired pneumonia of mild to moderate severity. Telithromycin prevents bacteria from growing, by interfering with their protein synthesis. Telithromycin binds to the subunit 50S of the bacterial ribosome, and blocks the progression of the growing polypeptide chain.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 12.32 mL | 61.58 mL | 123.15 mL |
| 0.5 mM | 2.46 mL | 12.32 mL | 24.63 mL |
| 1 mM | 1.23 mL | 6.16 mL | 12.32 mL |
| 5 mM | 0.25 mL | 1.23 mL | 2.46 mL |
*The above data is based on the productmolecular weight 812. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A11664 |
|---|---|
| CAS No. | 191114-48-4 |
| Formula | C43H65N5O10 |
| M. Wt | 812 |
| Purity | >98% |
| SMILES | CC[[email protected]]1[[email protected]]2([[email protected]@H]([[email protected]](C(=O)[[email protected]@H](C[[email protected]@]([[email protected]@H]([[email protected]](C(=O)[[email protected]](C(=O)O1)C)C)O[[email protected]]3[[email protected]@H]([[email protected]](C[[email protected]](O3)C)N(C)C)O)(C)OC)C)C)N(C(=O)O2)CCCCN4C=C(N=C4)C5=CN=CC=C5)C |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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