Tesevatinib
Important Notice: For research use only. We do not sell to patients.
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Important Notice: For research use only. We do not sell to patients.
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Discription | Tesevatinib (XL-647; EXEL-7647; KD-019) is an orally available, multi-target tyrosine kinase inhibitor; inhibits EGFR, ErbB2, KDR, Flt4 and EphB4 kinase with IC50s of 0.3, 16, 1.5, 8.7, and 1.4 nM. | ||
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Catalog Num | A21875 |
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Formula | C24H25Cl2FN4O2 |
Molecular Weight | 491.39 |
CAS Number | 781613-23-8 |
SMILES | [H][C@@]12[C@@](C[C@@H](COC3=CC4=C(C(NC5=C(F)C(Cl)=C(Cl)C=C5)=NC=N4)C=C3OC)C2)([H])CN(C)C1 |
Synonyms | XL-647, XL647, XL 647; EXEL-7647, EXEL7647, EXEL 7647; KD-019, KD019, KD 019 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2