Membrane Transporters-Ion Channels

HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3).

RF9 is a potent and selective Neuropeptide FF receptor antagonist, with Kis of 58??5 and 75??9 nM for hNPFF1R and hNPFF2R, respectively.

JNJ-31020028 is a novel, selective, brain-penetrant neuropeptide Y Y2 receptor antagonist

L 152804 is an orally active and selective neuropeptide Y Y5 receptor (NPY5-R) antagonist, with a Ki of 26 nM for hY5. L 152804 causes weight loss in diet-induced obese mice by modulating food intake and energy expenditure.