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Membrane Transporters-Ion Channels
Membrane Transporters-Ion Channels
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JT010 is a potent agonist of TRPA1 with an EC50 of 0.65 nM.
kainate receptors agonist
SYM 2081 is a high-affinity ligand and potent, selective agonist of kainate receptors, inhibits [3H]-kainate binding with an IC50 of 35 nM, almost 3000- and 200-fold selectivity for kainate receptors over AMPA and NMDA receptors respectively.
L-type Ca2+ channel agonist
(S)-(-)-Bay-K-8644 is an agonist of L-type Ca2+ channel. (S)-(-)-Bay-K-8644 activates Ba2+ currents (IBa) (EC50=32 nM).
(S)-(-)-5-Fluorowillardiine is a potent and specific AMPAR agonist.
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