Endothelin Receptors

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  1. ETBR antagonist

    IRL-2500 is a potent, selective ETBR antagonist. It shows some selectivity for ETB receptors (IC50 values are 1.3 and 94 nM for ETB and ETA receptors respectively).
  2. endothelin receptor type B (ETB) agonist

    IRL-1620 is a potent and selective endothelin receptor type B (ETB) agonist with a Ki of 16 pM.

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