Leukotriene Receptor

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  1. LTB4 receptor antagonist

    Amelubant (BIIL 284) is a potent, oral and long acting LTB4 receptor antagonist.
  2. cysteinyl-leukotriene antagonist

    Iralukast is a cysteinyl-leukotriene antagonist (CysLT) with a pKi of 7.8 for CysLT1.
  3. Leukotriene B4 Receptor antagonist

    CP-105696 is a potent and selective Leukotriene B4 Receptor antagonist, with an IC50 of 8.42 nM.
  4. CysLT1/CysLT2 antagonist

    Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively.

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