MCHR1 (GPR24)

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  1. MCH-1 antagonist

    MCH-1 antagonist 1 is a potent melanin concentrating hormone (MCH-1) antagonist with a Ki of 2.6 nM. MCH-1 antagonist 1 also inhibits CYP3A4 with an IC50 of 10 μM.
  2. MCHR1 antagonist

    SNAP 94847 is a novel, high affinity selective melanin-concentrating hormonereceptor1 (MCHR1) antagonist with (Ki= 2.2 nM, Kd=530 pM), it displays >80-fold and >500-fold selectivity over MCHα1A and MCHD2 receptors respectively.
  3. MCH1 receptor antagonist

    ALB-127158(a) is a potent and selective melanin concentrating hormone 1 (MCH1) receptor antagonist.

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