Melatonin Receptors

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  1. melanocortin receptor (MR) agonist

    AP1189 is a biased agonist at receptors MC1 and MC3. AP1189 reduced cytokine release, an effect reliant on both MC1 and MC3 as evident from the use of Mc1r(-/-) and Mc3r(-/-) macrophages.
  2. Melatonin receptor agonist

    ACH-000143 is a potent and peripherally preferred melatonin receptor agonist.

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